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Sintlife
Mouldable Bone Substitute
SINTlife Putty is a synthetic fully resorbable graft made of magnesium substituted hydroxyapatite nano-crystals.
Mimicking nature, magnesium ions are introduced into apatite crystal cells replicating the same positioning and composition as found in the mineral phase of human bone, making this the obvious formula for bone regeneration.
Sintlife
TECHNICAL SPECIFICATIONS
Mg-substituted apatite: just as nature designed it
It has been demonstrated that the presence of Mg2+ enables the hydroxyapatite crystal cell structure to become unstable and biologically active, promoting rapid cell-mediated material resorption, bone formation and remodelling.
In addition, Mg2+ substituted apatite displays improved surface properties: the biomaterial effectively interacts with water molecules* to rapidly capture the key proteins involved in osteogenesis.
*Bertinetti et al. Langmuir (2009)
Synchronized process: material resorption and new bone formation
SINTlife is a unique material that interacts with bone-forming cells and promotes deposition of new bone tissue. Thanks to its specific biomimetic chemical composition, nano-structure and surface properties, SINTlife is remodelled and resorbed by cellular action over a period of 6-18 months, allowing for sufficient biostimulative scaffold to remain during the formation and maturation of new bone.
During the remodelling phase, osteoclastic resorption and osteoblastic osteogenenetic activities are seen around the remaining SINTlife particles*, up to a complete bone regeneration. As a result, SINTlife leads to a physiological, rapid and effective repair.
*Landi et al., J. Mater Sci: Mater Med (2008)
Sintlife
INDICATIONS
Clinical applications
SINTlife is designed for use in a broad range of procedures, such as:
SINTlife may be combined with autologous bone, blood, bone marrow or growth factors.
SINTlife is not intended to modify or replace standard procedures for the treatment of bone defects, but for filling bony voids or gaps of the skeletal system, that are not intrinsic to the stability of the bony structure. It must be used with appropriate stabilising hardware.
Sintlife
SHAPES AND SIZES
SINTlife Spine is available with the following codes:
| Sintlife spine | |||||
| Code | Description | Quantity | |||
|---|---|---|---|---|---|
| PFS015057-08-00 | Putty (1,5 cc syringe) | 1 | |||
| PFS015057-04-00 | Putty (2,5 cc syringe) | 1 | |||
| PFS015057-05-00 | Putty (5 cc syringe) | 1 | |||
Sintlife Ortho is available with the following codes:
| Sintlife Ortho (*provided with cannula) | ||||||
| Code | Description | Quantity | ||||
|---|---|---|---|---|---|---|
| PFS015056-01-00 | Putty (1 cc syringe) | 1 | ||||
| PFS015056-02-00 | Putty (2.5 cc syringe)* | 1 | ||||
| PFS015056-00-00 | Putty (5 cc syringe)* | 1 | ||||
| PFS015056-05-00 | Putty (10 cc syringe)* | 1 | ||||
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