Finceramica’s research activity is aligned with the innovation in biomimetic regenerative medicine of today and tomorrow.

Finceramica and its Commercial Partners have combined their strengths to provide innovative and effective therapeutic solutions designed to satisfy the needs of both the surgeon and patient. Finceramica has specialised in the development and technology of bio-ceramic materials. Together with Commercial Partners, Finceramica maintains a constant information exchange with the leading neurosurgeons.

Finceramica Team works in complete synergy with Commercial Partners to provide the surgeon with state-of-the-art technical support during the entire CustomBone Service process.

Cranial reconstruction is a complex surgical procedure associated with high morbidity rates, regardless of the material chosen. Different solutions have been developed and deeply investigated over the years to find out the “ideal material”, which might be biocompatible and able to osteointegrate with the host bone, mechanically resistant, osteoconductive and resistant to infection.

CustomBone Service (CBS) is a custom-made cranial implant made of hydroxyapatite (HA), a Ca/P-derivative with chemico-physical features and a 3D porous structure which resembles the mineral component and structure of human bone. Compared to other alloplastic alternatives on the market (i.e. PMMA, PEEK, Titanium), these peculiar properties make CustomBone Service the ideal candidate for replacing cranial bone defect in a physiological manner.

The unique properties of bio-ceramic material

• Macro-and micro-porosity;
• Chemical and morphological biomimetic structure similar to the mineral component of human bone, enhancing osteointegration through progenitor bone cells migration and adhesion;
• Highly bio-compatible material, showing a reduce post-op infection incidence than titanium-based implants (*);
• The porous structure and hydrophilic surface allow for loco-regional use of antibiotics, when deemed clinically useful by the surgeon (**, ***);
• Natural aesthetic result leading to high level of patient satisfaction;
• Completely radiolucent allowing for MRI diagnostics without artifacts.



(*) Lindner D, Schlothofer-Schumann K, Kern BC, Marx O, Müns A, Meixensberger J. Cranioplasty using custom-made hydroxyapatite versus titanium: a randomized clinical trial. J Neurosurg. 2017 Jan;126(1):175-183.
(**) Nataloni A., Martinetti R., Staffa G., Servadei F. Rifamicine release from porous hydroxyapatite as anti-infection prophylactic for the cranial theca reconstruction
(***) Iaccarino C, Mattogno PP, Zanotti B, Bellocchi S, Verlicchi A, Viaroli E, Pastorello G, SGULò F, Ghadirpour R, Servadei F Septic complication following porous hydroxyapatite cranioplasty: prosthesis retention management J Neurosurg Sci. 2016 May 13

CustomBone Service is intended to replace bone voids in the cranial and/or craniofacial skeleton. This device may be used both for adult and paediatric patients (for children above 2 years of age).

CustomBone custom-made implants are suitable for reconstructing cranial defects resulting from:

• Trauma and vascular pathologies, either associated or non-associated to cranial decompression;
• Removal of tumours;
• Reabsorption of autologous bone;
• Rejection of other prosthetic materials;
• Congenital malformations.