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ENGIpore

sostituto osseo performato

ENGIpore-sostituto osseo performato

Architettura biomimetica ideale

ENGIpore è un innovativo biomateriale poroso a base di idrossiapatite con una struttura trabecolare del tutto simile a quella dell’osso naturale. È un sostituto osseo biomimetico pronto all’uso, prodotto con i più alti standard qualitativi e privo di qualsiasi rischio di trasmissione virale.

ENGIpore è disponibile in diversi formati per applicazioni in chirurgia ortopedia e chirurgia spinale (fusione vertebrale)

Scheda prodotto (download pdf)

Elevata porosità

L’osteointegrazione del biomateriale e la neossificazione sono garantite da una struttura altamente porosa definita e controllata a livello macro, micro e di interconnessione dei pori.

La porosità totale di ENGIpore può arrivare fino al 90%, favorendo un rapido assorbimento dei fluidi biologici e delle molecole segnale e permettendo la rapida colonizzazione cellulare indispensabile per una buona rigenerazione ossea.

Nonostante l’elevata porosità, ENGIpore è in grado di resistere a carichi in compressione al pari dell’osso spongioso.

Rapida osteointegrazione

Una volta applicato in situ, ENGIpore assorbe rapidamente le proteine bio-attive, i fattori di crescita e le cellule indifferenziate contenute nei liquidi fisiologici, elementi indispensabili per una rapida ed efficace rigenerazione ossea.

Applicazioni cliniche

ENGIpore è stato progettato per essere applicato in varie procedure chirurgiche:

021-indicazioni - indicazioni

ENGIpore può essere miscelato con osso autologo, fuidi biologici, concentrato midollare e fattori di crescita.

ENGIpore va inteso come un riempitivo di cavità o lacune ossee. Non deve sostituire le procedure standard per il trattamento dei difetti ossei. Deve essere utilizzato con gli opportuni mezzi di sintesi e stabilizzazione meccanica.

ENGIpore Ortho è disponibile con i seguenti codici:

Chips

codice
descrizione
PFS015005-40-00
1,0 - 2,5 mm - 5 cc
PFS015005-41-00
1,0 - 2,5 mm - 15 cc
PFS015005-50-00
2,5 - 4,0 mm - 5 cc
PFS015005-51-00
2,5 - 4,0 mm - 15 cc
PFS015005-52-00
2,5 - 4,0 mm - 30 cc

Cunei

codice
descrizione
PFS015005-30-00
40x30 mm, incl. 11° (h 10,5 mm)
PFS015005-31-00
40x30 mm, incl. 15° (h 13,5 mm)
PFS015005-32-00
40x30 mm, incl. 19° (h 16,5 mm)
PFS015006-19-00
30x15 mm, incl. 11° - 2 pcs. (h 8,5 mm)
PFS015006-20-00
30x15 mm, incl. 15° - 2 pcs. (h 10,5 mm)
PFS015006-25-00
30x15 mm, incl. 9° - 2 pcs. (h 7,5 mm)

Blocchetti

codice
descrizione
PFS015005-21-00
10x10x12 mm
PFS015005-22-00
20x10x12 mm
PFS015005-23-00
30x20x12 mm
PFS015005-24-00
40x20x12 mm

Cilindri cavi

codice
descrizione
PFS015008-01-00
ED = 12 mm ID = 3 mm h = 40 mm
PFS015008-02-00
ED = 15 mm ID = 3 mm h = 40 mm)
PFS015008-03-00
ED = 18 mm ID = 3 mm h = 40 mm)

SH

codice
descrizione
PFS015005-77-00
SH-Small 38 x 25 x 17 - 13 mm
PFS015005-76-00
SH-Medium 41 x 28 x 18 - 14 mm
PFS015005-75-00
SH-Large 45 x 30 x 20 - 15 mm

ENGIpore Spine è disponibile con i seguenti codici:

Chips

codice
descrizione
PFS015009-01-00
1,0 - 2,5 mm - 5 cc
PFS015009-02-00
1,0 - 2,5 mm - 15 cc
PFS015009-03-00
2,5 - 4,0 mm - 5 cc
PFS015009-04-00
2,5 - 4,0 mm - 15 cc
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    Progress in Neuroscience, Vol. 3, N 1-4, 2015
  3. Barbanti Brodano G, et al. (2015) “A post-market surveillance analysis of the safety of hydroxyapatite-derived products as bone graft extenders or substitutes for spine fusion.”
    Eur Rev Med Pharmacol Sci 19(19):3548–3555
  4. Barbanera A, et al. (2013) “Potential applications of synthetic bioceramic bone graft substitute in spinal surgery.”
    Progress in Neuroscience 97–104
  5. Manfrini M, et al. (2013) “Mesenchymal stem cells from patients to assay bone graft substitutes.”
    J Cell Physiol 228(6):1229–1237
  6. Barbanti Brodano G, et al. (2012) “Human mesenchymal stem cells and biomaterials interaction: a promising synergy to improve spine fusion.”
    European Spine Journal 21(S1):3–9
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ENGIpore