Message intended for healthcare professionals only
We would like to inform you about a recent clinical paper.
The paper titled Complications and cosmetic outcomes of materials used in cranioplasty following decompressive craniectomy-a systematic review, pairwise meta-analysis, and network meta-analysis1 (https://pubmed.ncbi.nlm.nih.gov/35593924/) is aimed to compares cosmetic outcomes and complications of autologous bone grafts and alloplasts used for cranioplasty following DC.
HA had the lowest infection and reoperation rate in respect to other alloplasts (PEEK, PMMA, Titanium, CaP and Porous Polyethylene) and autologous bone (see Table below).
HA ranked the highest in the network (in overall complication, infections, hematoma and reoperation), and has shown osteointegrative properties 2 and low incidence of complications in large cohorts 3.
References:
[1] Jakob V. E. Gerstl, Luis F. Rendon, Shane M. Burke, Joanne Doucette, Rania A. Mekary, Timothy R. Smith. “Complications and cosmetic outcomes of materials used in cranioplasty following decompressive craniectomy-a systematic review, pairwise meta-analysis, and network meta-analysis” Acta Neurochirurgica (2022) 164:3075–3090 (https://pubmed.ncbi.nlm.nih.gov/35593924/)
[2] Maenhoudt W, Hallaert G, Kalala JP, Baert E, Dewaele F, Bauters W, Van Roost D “Hydroxyapatite cranioplasty: a retrospective evaluation of osteointegration in 17 cases” Acta Neurochir (2018) 160:2117–2124 (https://pubmed.ncbi.nlm.nih.gov/30276548/)
[3] Stefini R, Esposito G, Zanotti B, Iaccarino C, Fontanella MM, Servadei F “Use of “custom made” porous hydroxyapatite implants for cranioplasty: postoperative analysis of complications in 1549 patients” Surg Neurol Int (2013) 4:12. (https://pubmed.ncbi.nlm.nih.gov/23493459/)