ENGIpore

pre-formed bone substitute

ENGIpore-pre-formed bone substitute

Micro, macro and interconnected porosity

This biomaterial has a unique, controlled micro and macro porosity along with an effective structure that supports rapid bone ingrowth and formation.

Its unique structure gives ENGIpore a porosity of almost 90%, and this guarantees an easy access of cells, biological fluids, and attracting the correct molecules throughout the bone substitute.

Despite the highly porous structure, ENGIpore is able to resist the compression forces associated with natural bone.

Rapid osteointegration

Once applied in situ, ENGIpore rapidly absorbs all bio-active proteins, growth factors and bone precursor cells contained in the physiological fluids. This encourages and begins the biological cascade leading to effective bone regeneration.

Clinical applications

ENGIpore is designed for use in a broad range of procedures, such as:

021-indicazioni - indications

ENGIpore may be combined with autologous bone, blood, bone marrow or growth factors.

ENGIpore is not intended to modify or replace standard procedures for the treatment of bone defects, but for filling bony voids or gaps of the skeletal system, that are not intrinsic to the stability of the bony structure. It must be used with appropriate stabilising hardware.

ENGIpore Ortho is available with the following codes:

Chips

code
description
q.ty per Package
PFS015005-40-00
Chips (size 1,0-2,5 mm)
5 cc
PFS015005-41-00
Chips (size 1,0-2,5 mm)
15 cc
PFS015005-50-00
Chips (size 2,5-4,0 mm)
5 cc
PFS015005-51-00
Chips (size 2,5-4,0 mm)
15 cc
PFS015005-52-00
Chips (size 2,5-4,0 mm)
30 cc

Wedge

code
description
q.ty per Package
PFS015005-30-00
Cuneo (40x30 mm, incl. 11°)
1
PFS015005-31-00
Wedge (40x30 mm, incl. 15°)
1
PFS015005-32-00
Cuneo (40x30 mm,, incl. 19°)
1
PFS015006-19-00
Wedge (30x15 mm, incl. 11°)
2
PFS015006-20-00
Wedge (30x15 mm, incl. 15°)
2
PFS015006-25-00
Wedge (30x15 mm, incl. 9°)
2

 Block

code
description
q.ty per Package
PFS015005-21-00
Block (10x10x12 mm)
1
PFS015005-22-00
 Block (20x10x12 mm)
1
PFS015005-23-00
 Block (30x20x12 mm)
1
PFS015005-24-00
Blocchetto (40x20x12 mm)
1

Hollow Cylinder

code
description
q.ty per Package
PFS015008-01-00
Hollow Cylinder (øe = 12 mm øi = 3 mm H = 40 mm)
1
PFS015008-02-00
Hollow Cylinder (øe = 15 mm øi = 3 mm H = 40 mm)
1
PFS015008-03-00
Hollow Cylinder (øe = 18 mm øi = 3 mm H = 40 mm)
1
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  1. Giorgi P, et al. (2015) Use of a novel porous hydroxyapatite bone graft substitute in postero-lateral and interbody spinal fusion: clinical and radiographic analysis at 4 year follow up
    Progress in Neuroscience, Vol. 3, N 1-4, 2015
  2. Barbanti Brodano G, et al. (2015) “A post-market surveillance analysis of the safety of hydroxyapatite-derived products as bone graft extenders or substitutes for spine fusion.”
    Eur Rev Med Pharmacol Sci 19(19):3548–3555
  3. Barbanera A, et al. (2013) “Potential applications of synthetic bioceramic bone graft substitute in spinal surgery.”
    Progress in Neuroscience 97–104
  4. Manfrini M, et al. (2013) “Mesenchymal stem cells from patients to assay bone graft substitutes.”
    J Cell Physiol 228(6):1229–1237
  5. Barbanti Brodano G, et al. (2012) “Human mesenchymal stem cells and biomaterials interaction: a promising synergy to improve spine fusion.”
    European Spine Journal 21(S1):3–9
  6. Komlev VS, et al. (2010) “Biodegradation of porous calcium phosphate scaffolds in an ectopic bone formation model studied by X-ray computed microtomograph.”
    Eur Cell Mater 19(136):e46
ENGIpore